This patient has areas of depigmentation around the mouth, the upper limb, legs and trunk. He has vilitigo.
Vitiligo affects 1% of the population. Equal between males and females, although more females present to the skin clinic. Family history in 1/3 of patients.
They have Koebner's phenomenon - lesion appearing on the site of lesion.
When you see a patient like this, look for other features of autoimmune
Thyroid disorder - Hashimoto's thyroiditis, Graves' disease
Pallor - Pernicious anaemia
Pigmentation of buccal, skin crease, hypotension - Addison's disease
Tetany, cramps, paraesthesia, Chvostek's and Trousseau's sign - Idiopathic hypoparathyroidism
Fundus - diabetes mellitus
Lungs (fine crepts) - Fibrosing alveolitis
Jaundice - Chronic active hepatitis
Excoriation marks, xanthalesma, pigmentation - primary biliary cirrhosis
rash, arthritis, prox weakness - SLE, RA, dermatomyositis, polymyositis
Look out for polyglandular autoimmune disease
What are the 2 types ?
6 comments:
MEN Type 1 involves parathyroid, pituitary,pancreas, adrenal and thyroid glands(rare).
MEN type 2 involves Adrenal, Thyroid and Parathyroid glands.
polyglandular autoimmune disease is different from MEN. Good try though.
Type I- chronic mucocutaneous candidiasis, hypoparathyroidism and Addison's disease.
Type II- Addison's disease, insulin-dependent diabetes and thyroid disease(hyperthyroidism or hypothyroidism)
Type I(whitaker syndrome)occurs in childhood n rare.chronic mucocutaneous candidiasis,hypoparathyroidism n autoimmune adrenal insufficiency.
Type II(schmidt's syndrome)occurs in adulthood.Addison's disease,DM(TYPE 1),hypogonadism,throid disease,myasthenia gravis.
Yes !
Collectively I studied the discription about the patient of vitiligo and the comments of the persons on this blog impressed me to leave some words of my expressions
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