Monday, March 23, 2009

Argyll Robertson pupil



This is an interesting video I downloaded from youtube. I am sure it will be benefeficial for medical students to understand this.

I used to have problem remember when the pupil constricts and when it dilates till I heard this joke :
A prostitute will accomadate but will not react.

So in Argyll Robertson pupil(due to Neurosyphilis), the pupil will constrict to accomadation reflex but will not constrict to light - just as what the video showed.
It is due to damage to the periaqueductal area and is a classic sign.
The pupil is small, irregular and fixed to light but reactive to accomodation
Other causes of what perhaps incorrectly called AG pupils are pinealomas, diabetes, brainstem encephalitis, multiple sclerosis and Wernicke's encephalopathy. These conditions cause fixed semidilated pupils and sometimes unequal pupils; only a small, irregular, fixed pupil should be attributed to neurosyphilis.

I was fortunate, well unfortunate for the patient to have managed a case of neurosyphilis 2 years ago in Neurology . I still remembered the LP I did for the patient (as above) which showed VDRL positive in the LP. Patient actually improved after treated with Penicillin.

Now, the question I want to ask is - what if you get pupils which react to light but not to accomodation (reversed Argyll Robertson pupil). What is the cause ?
Clue : It occured in 1920s


6 comments:

Anonymous said...

Epidemic encephalitis lethargica or von Economo disease.

I would like to ask, apart from this disease, in what other cases we may observe this phenomenon...

Also, in what cases would lead u to perform the test on pupil...

Anonymous said...

encephalitis lethargia

Not too sure about other causes.

Anonymous said...

Encephalitis Lethargica

Wuchereria said...

Excellent ! All neurological examination should alert you to perform this or if you find ptosis or pupils which are small or irregular.

Dr.Surat Tanprawate said...

Could i ask you that why the pupils are small if syphilis effect to EWN. Why it is not large as it impair the parasympathetic partway.

medicalstudent said...

the Argyll Robertson pupil affect which eye in Tabes dorsalis?